PorteursAnne GeigerAffiliation porteursIRD-CIRAD-UMR 177, InterTryp, Montpellier

Malaria and sleeping sickness: molecular crosstalk between vector insects and their gut microbiome; search for genes controlling vector competence

The project aims to decipher the molecular cross-talk between a) the tsetse fly, its intestinal microflora and the trypanosome, and b) the anopheles, its microflora and the plasmodium. A global (metatranscriptomic and microbial) and comparative analysis will be performed between non infected and infected insect vectors, and genes differentially expressed with reference to the infection process will be identified. These genes may become targets for blocking the insect vector competence.

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