PorteursJames McKayAffiliation porteursIARC-Lyon Génétique Humaine

Genomic analysis of inherited lung cancer

We propose the genomic analysis of 200 lung tumours resected from patients with a high a priori likelihood of genetic susceptibility based on age of onset or family history. Complementary germ-line studies in these patients with this rare phenotype are ongoing. A novel combined analysis of somatic and germ-line genomic data will be used to evaluate the consequence of germ-line variation on the tumour’s characteristics and assist identification of novel susceptibility alleles for lung cancer.

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