ARTbio is the bioinformatics platform of the Institut de Biologie Paris Seine, a 600-members research institute located in the campus Jussieu of Sorbonne University. ARTbio is open to all biologists and doctors from IBPS, Sorbonne University, any academic structure, and private companies. The main objective of ARTbio is to help Biologists and medical doctors in their computational approaches required to analyse big data in genomics, medical research, neurobiology, imaging, etc. This objective is tackled through 3 lines: Services (Services in analysis or collaborative projects, online web services), Teaching (Companionship, training days, seminars, documentation) and Development (tools, workflows, analysis environments, storage, etc).

Expertise

We have a core expertise in high throughput sequencing approaches to study genetics and gene regulation, epigenetics, small RNA biology and viruses metagenomics.

We use statistics for significance testing and classification using probabilistic, bayesian and artificial intelligence approaches.

We are currently focusing on single-cell RNAseq and rare genetic variant analyses.

We ensure project quality and optimal interaction with users by using Continuous Integration technologies and the AGILE guidelines.

Equipments

The informatics structure of ARTbio platform hosts storage services with 50To of capacity and web services : Mississippi Galaxy public server as well as Galaxy, Rstudio and Jupyterhub servers dedicated to ARTbio projects.

Devlopment

• Metavisitor, suite of Galaxy tools for simple and rapid detection and discovery of viruses in deep sequence data
• GalaxyKickStart, an Ansible playbook for automated deployment of Galaxy servers
• ARTbio Galaxy tools and workflows are in open access in our ARTbio/tool-artbio GitHub repository as well as in the main galaxy toolshed