LIGAN
Sarah Meulebrouck et al.
Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function
Nature Communications 2024, vol. 15, issue 1
doi: 10.1038/s41467-024-51004-6
Orthis Saha et al.
The Alzheimer’s disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons
Molecular Psychiatry 2024, vol. 29, issue 9
doi: 10.1038/s41380-024-02502-y
Lise Folon et al.
Pathogenic, Total Loss-of-Function DYRK1B Variants Cause Monogenic Obesity Associated With Type 2 Diabetes
Diabetes Care 2024, vol. 47, issue 3
doi: 10.2337/dc23-1851
Arnaud Dance et al.
Exploring the role of purinergic receptor P2RY1 in type 2 diabetes risk and pathophysiology: Insights from human functional genomics
Molecular Metabolism 2023, vol. 79
doi: 10.1016/j.molmet.2023.101867
Youssef Kouidrat et al.
Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: Lessons for precision medicine
Diabetes & Metabolism 2023, vol. 50, issue 1
doi: 10.1016/j.diabet.2023.101507
Sarah Meulebrouck et al.
Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas
Diabetologia 2023, vol. 67, issue 2
doi: 10.1007/s00125-023-06035-x
Ana Raquel Melo de Farias et al.
Amyloid-Beta Peptides Trigger Premature Functional and Gene Expression Alterations in Human-Induced Neurons
Biomedicines 2023, vol. 11, issue 9
doi: 10.3390/biomedicines11092564
Wenwen Gao et al.
Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity
Nature Metabolism 2023, vol. 5, issue 10
doi: 10.1038/s42255-023-00889-6
Frédérik Oger et al.
Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
iScience 2023, vol. 26, issue 7
doi: 10.1016/j.isci.2023.107231
Frédérik Oger et al.
β-Cell–Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion
Diabetes 2023, vol. 72, issue 8
doi: 10.2337/db22-0604