Sélection 2015

Chevalier B et al.
miR-34/449 control apical actin network formation during multicilio genesis through small GTPase pathways.
Nat Commun. (2015)
doi: 10.1038/ncomms9386

Laustriat D. et al.
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin
Mol Ther Nucleic Acids. 2015, 4p. e26
doi: 10.1038/mtna.2015.35

Mirzaa GM et al.
Characterisation of mutations of the phosphoinositide-3-kinase regulatory subunit, PIK3R2, in perisylvian polymicrogyria: a next-generation sequencing study.
Lancet Neurol. (2015)
doi: 10.1016/S1474-4422(15)00278-1

Tourneau, C.L et al.
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
Lancet Oncol.
doi: 10.1016/S1470-2045(15)00188-6

Portal MM. et al.
TARDIS, a targeted RNA directional sequencing method for rare RNA discovery.
Nat Protoc. (2015) (12):1915-38.
doi: 10.1038/nprot.2015.120

Thierry A. et al.
Macrotene chromosomes provide insights to a new mechanism of high-order gene amplification in eukaryotes.
Nat Commun. (2015) 6:6154.
doi: 10.1038/ncomms7154

Crottès D.et al.
SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness.
Cancer Res. 76(3):607-18.
doi: 10.1158/0008-5472.CAN-15-1465

Carradec Q. et al.
Primary and secondary siRNA synthesis triggered by RNAs from food bacteria in the ciliate Paramecium tetraurelia.
Nucleic Acids Res. (2015) 43(3):1818-33.
doi: 10.1093/nar/gku1331

Prasad MK et al.
A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement.
J Med Genet. Epub 2015 Oct 26.
doi: 10.1136/jmedgenet-2015-103302

Boulay AC. et al.
Immune quiescence of the brain is set by astroglial connexin 43.
J Neurosci. (2015)
doi: 10.1523/JNEUROSCI.2575-14.2015