Publications Sélection 2015

Tourneau, C.L et al.
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
Lancet Oncol.
doi: 10.1016/S1470-2045(15)00188-6

Portal MM. et al.
TARDIS, a targeted RNA directional sequencing method for rare RNA discovery.
Nat Protoc. (2015) (12):1915-38.
doi: 10.1038/nprot.2015.120

Thierry A. et al.
Macrotene chromosomes provide insights to a new mechanism of high-order gene amplification in eukaryotes.
Nat Commun. (2015) 6:6154.
doi: 10.1038/ncomms7154

Crottès D.et al.
SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness.
Cancer Res. 76(3):607-18.
doi: 10.1158/0008-5472.CAN-15-1465

Carradec Q. et al.
Primary and secondary siRNA synthesis triggered by RNAs from food bacteria in the ciliate Paramecium tetraurelia.
Nucleic Acids Res. (2015) 43(3):1818-33.
doi: 10.1093/nar/gku1331

Prasad MK et al.
A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement.
J Med Genet. Epub 2015 Oct 26.
doi: 10.1136/jmedgenet-2015-103302

Boulay AC. et al.
Immune quiescence of the brain is set by astroglial connexin 43.
J Neurosci. (2015)
doi: 10.1523/JNEUROSCI.2575-14.2015

Kopylova E. et al.
Deciphering metatranscriptomic data.
Methods in molecular biology (Clifton, NJ), (2015) 1269:279-291.
doi: 10.1007/978-1-4939-2291-8_17

Al Adhami H et al.
A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation.
Genome Res. (2015)
doi: 10.1101/gr.175919.114

Laurette P. et al.
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.
Elife. (2015) 4.
doi: 10.7554/eLife.06857

Roux PF.et al.
Combined QTL and selective sweep mappings with coding SNP annotation and cis-eQTL analysis revealed PARK2 and JAG2 as new candidate genes for adiposity regulation.
G3 (Bethesda). (2015) 5(4):517-29.
doi: 10.1534/g3.115.016865

Vanhille L. et al.
(2015). High-throughput and quantitative assessment of enhancer activity in mammals by CapStarr-seq.
Nat Commun.
doi: 10.1038/ncomms7905

Zacarias-Cabeza,J. et al.
Transcription-Dependent Generation of a Specialized Chromatin Structure at the TCRbeta Locus.
J. Immunol. (2015) 194, 3432-3443.
doi: 10.4049/jimmunol.1400789

Rodier G. et al.
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions.
Cell Rep. (2015) 11:220-33
doi: doi.org/10.1016/j.celrep.2015.03.024

Madoui MA. et al.
Genome assembly using Nanopore-guided long and error-free DNA reads
Bmc Genomics,. 2015, 16:327.
doi: 10.1186/s12864-015-1519-z

Saintamand A. et al.
Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion.
Nat Commun. (2015) 6:7084.
doi: 10.1038/ncomms8084

de Vargas C. et al.
Tara Oceans C,Eukaryotic plankton diversity in the sunlit ocean
Science. 2015, 348(6237):1261605.
doi: 10.1126/science.1261605

Chen H et al.
Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency.
Nat Commun. (2015)
doi: 10.1038/ncomms8095

Pesant S. et al.
Open science resources for the discovery and analysis of Tara Oceans data
Scientific data. 2015 2:150023.
doi: 10.1038/sdata.2015.23

Vembar SS et al.
A. The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages.
Genome Biol. (2015)
doi: 10.1186/s13059-015-0771-5

Eleveld, T.F. et al.
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
Nature Genetics.
doi: 10.1038/ng.3333

Grünewald TGP. et al.
Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite.
Nature Genetics (2015)
doi: 10.1038/ng.3363

Legendre M. et al.
In-depth study of Mollivirus sibericum, a new 30,000-y-old giant virus infecting Acanthamoeba
Proc Nat Acad Sci U.S.A. 2015 112(38) :E5327-E5335.
doi: 10.1073/pnas.1510795112

Chevalier B et al.
miR-34/449 control apical actin network formation during multicilio genesis through small GTPase pathways.
Nat Commun. (2015)
doi: 10.1038/ncomms9386

Laustriat D. et al.
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin
Mol Ther Nucleic Acids. 2015, 4p. e26
doi: 10.1038/mtna.2015.35

Mirzaa GM et al.
Characterisation of mutations of the phosphoinositide-3-kinase regulatory subunit, PIK3R2, in perisylvian polymicrogyria: a next-generation sequencing study.
Lancet Neurol. (2015)
doi: 10.1016/S1474-4422(15)00278-1