Sheep and Goats were domesticated ~10,000 years ago from their wild ancestors: Asiatic mouflon and bezoar. Currently, there are more than 2,300 sheep and goat breeds worldwide, and most of them are adapted to various environments and/or selected for production traits. Through the generation of domestic breeds sequence data and their analysis together with existing data, this collaborative project aims at exploring genetic diversity, detecting selective sweeps and characterizing functional mutations in various goat and sheep breeds through single base, copy number and structural variants analysis.
Publications :
- Isaäc J Nijman et al. Geographical contrasts of Y‐chromosomal haplogroups from wild and domestic goats reveal ancient migrations and recent introgressions. Molecular Ecology 2022, vol 31, issue 16
- Aurélie Allais-Bonnet et al. Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae Molecular Biology and Evolution 2021, vol 38, issue 6
- Laure Denoyelle et al. VarGoats project: a dataset of 1159 whole-genome sequences to dissect Capra hircus global diversity Genetics Selection Evolution 2021, vol. 53, issue 1