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Call for proposals: « Large-scale sequencing projects »


2016 CALL FOR PROPOSALS « Large-scale sequencing projects » is now closed.

The mission of the France Génomique infrastructure is to provide genomics services to the French scientific community. In particular, this involves establishing genome reference sequences of particular interest in fundamental or applied research, and the use of high throughput sequencing methods notably for comparative or functional approaches in the areas of human genomics, environmental genomics and metagenomics.

In the context of this mission, France Génomique will devote a large part of its sequencing capacity and associated expertise to several ambitious large-scale projects. These will be projects submitted by public research laboratories (CNRS, INSERM, INRA, CEA, CIRAD, IRD, Universities, Foundations…), and they will be carried out by the platforms of the CEA "F. Jacob Institute of Biology" (Genoscope and CNRGH). The projects may also involve collaborations with foreign institutions, notably in Europe. The consumables costs for these projects may be covered in part or in full by France Génomique.

These large-scale projects will be developed in collaboration with the F. Jacob Institute of Biology (IBFJ), on the basis of a written agreement. The IBFJ will advise collaborators on the strategy that appears to best correspond to the project, based on the technologies available (Sanger, Ion Torrent, Illumina HiSeq and MiSeq, Oxford Nanopore). The project partners (IG and collaborators) will define together the practical conditions for undertaking the experimental work. The data resulting from this collaboration will be jointly owned by the partners, who will define the method of dissemination of results and any measures for protection of intellectual property, in agreement with their institutions and in accordance with usual practices in the scientific community. In particular, the data will be put into the public domain: as a general rule, the assembled sequences will be submitted to public data banks 180 days after they have been provided by the IBFJ to the collaborating institution, and in conformance with international rules and practices.

To be eligible, projects must involve de novo sequencing of large whole genomes, and sequencing of a large number of individuals from a species for which the reference genome is known, and more generally from DNA collections that require a very large-scale sequencing approach (e.g. 10 or more Illumina HiSeq flow cells). The study should also involve organisms of major scientific interest, or of major medical or financial interest. Projects involving populations of organisms (metagenome, biological diversity), environmental genomics or population genomics are encouraged.

This call targets only those projects that require large-scale sequencing, e.g. more than 10 flow cells for projects that use Illumina HiSeq technology. Smaller-scale projects, which can be funded and undertaken by other means, are not eligible for submission to this call; instead they should be submitted to the continuous submission scheme on the France Génomique website (https://www.france-genomique.org/spip/spip.php?article92&lang=en) to be undertaken with co-funding from the applicant laboratory.

Project applications should be submitted in English, using the template below..
Word - 26 kb

Download the application form template

Timetable and evaluation procedures :

The results will be announced in February 2017. Applications will be evaluated by the France Génomique Scientific Review Committee (https://www.france-genomique.org/spip/spip.php?article89&lang=en).

Projects will be evaluated according to the following criteria:
-  scientific interest
-  feasibility
-  expected impact on the scientific community (national and international)
-  international context
-  ability of applicants to obtain the necessary biological material rapidly
-  ability of applicants to perform the bioinformatics analysis
-  ability of applicants to use and publish the sequencing results

Deadline for applications: Tuesday, 20 Septembre 2016 (midnight).

To submit your project: Click here to upload your completed application (format PDF)

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